1.e3 d6

Possible lines are:

2.Qf3 f5 (or 2...Nf6, with 3.Bd3 Bg4 4.Bf5 Ne4),

2.Nf3 Bg4 followed by 3.Bb5 c6 or 3.Nc3 Nf6,

2.Qh5 g6 3.Nc3,

2.Nc3.